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Peripheral Venous Disease

Peripheral venous disease is the blockage of a vein by a blood clot. It can happen anywhere in the body but is most common in the arms and legs. It is caused by injury, infection, a long bed rest or illness, recent major surgery, pregnancy, or being overweight.
Illustration of normal veins vs varicose veins
Illustration of May-Thurner syndrome (MTS)

Click on image to expand.

What are the symptoms of peripheral venous disease?

As functional venous valves are required to provide for efficient blood return from the lower extremities, this condition typically affects the legs. If the impaired vein function causes significant symptoms, such as swelling and ulcer formation, it is referred to as chronic venous disease. It is sometimes called chronic peripheral venous insufficiency and should not be confused with post-thrombotic syndrome in which the deep veins have been damaged by previous deep vein thrombosis.

Signs and symptoms may include:

  • Varicose veins
  • Chronic leg edema and skin changes
  • Restlessness
  • Itching
  • Cramping
  • Diabetic Ulcers
  • Heaviness or tiredness
  • Open skin sores

Did you know?

About 50% of patients with severe venous reflux disease have central vein compression or May-Thurner syndrome, which is easily treated with venous stenting treatment. If you’ve had previous vein ablations and are still experiencing swelling and/or pain you may have central vein compression. Call us for a consultation. We can help.

Schedule a personalized assessment and find out your treatment options.

Dr. Moinakhtar Lala and Dr. Mehran J. Khorsandi of CACVI

Dr. Moinakhtar Lala and Dr. Mehran J. Khorsandi

Meet Your Specialists


The Center for Advanced Cardiac and Vascular Interventions (CACVI) is led by Dr. Khorsandi and Dr. Lala, who have over thirty years of practice with over 15,000 successful vascular and cardiac procedures performed. Our physicians are determined to provide each patient with unparalleled expertise and compassionate care as they work diligently to improve your health.
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